Most of the case we go with full bridge topology with HF transformer to achieve high voltage ratio (~16 times) where as with simple boost converter we can achieve 6 to 7 times (~85% of Duty cycle) ,

So , Is there any alternative way to achieve high voltage ratio like 16~18 times of input voltage? I know Voltage Multiplier Boost Converter, but never implemented in any of my design. So wanted to know how much high voltage ratio can be able to achieve by this topology? Why this is not broadly addressed in the industries like phase shifted full bridge topology? If any one can write few line about this topology's advantage and disadvantages will be greatly appreciate...Also Looking for experts comments to know best suitable way to achieve such a higher voltage ratio with power rating of let say 1kW to 5kW range...

Thanks to all in advance.